elcome to dbPHSP (http://jjwanglab.org/dbpshp
). The database contained curated publications about positive selection in different human populations, which consisted of over 15,000 loci from either publications attempting to study positively selected genomic locus and gene related to specific functions/traits/diseases, or publications to detect the genome-wide selective signals with different statistical methods.
It also includes 15 statistical terms for each single nucleotide polymorphism site from the HapMap III and 1000 Genomes Project genotyping data. These attributes include variant allele frequency, variant heterozygosity, within population diversity, haplotype homozygosity, long-range haplotypes, pairwise population differentiation and evolutionary conservation. We also provided interactive pages for visualization and annotation of different selective signals.
- Literature-based region with recent positive selection evidence for different human populations;
- 15 statistical terms computed by different statistical methods which indicate the selective signals;
- Dynamic pages for filtering, visualization and annotation;
- Lightweight local files encapsulated by indexed VCF format;
- Web Services by RESTful interface.
Please cite the work from:
dbPSHP: a database of recent positive selection across human populations Nucleic Acids Research
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